A trypanosomal orthologue of an intermembrane space chaperone has a non-canonical function in biogenesis of the single mitochondrial inner membrane protein translocase.

Mitochondrial protein import is essential for Trypanosoma brucei across its life cycle and mediated by membrane-embedded heterooligomeric protein complexes, which mainly consist of trypanosomatid-specific subunits.However, trypanosomes contain orthologues of small Tim chaperones that escort hydrophobic proteins across the intermembrane space.Here w

read more



1-Prop-2-ynyl-1H-benzimidazol-2-amine

In the title compound, C10H9N3, the benzimidazol-2-amine and CH2—C[triple-bond]CH units are not coplanar, with a dihedral angle of 60.36° between HANDWARMER their mean planes.The crystal structure is stabilized by intermolecular N—H.N hydrogen bonding and π–π interactions [centroid–

read more